Research
Main Concepts and Applications
Research Interests and Expertise
Cardiovascular mechanics
Cardiac and vascular imaging
Devices and instrumentation
Systemic and microvascular hemodynamics monitoring and measurements
Novel therapeutic interventions to manage and prevent disease
Artificial blood, gas carriers
Plasma expanders
Drug delivery
Computer modeling and systems analysis
Diagnostic methods
Noninvasive instrumentation
Microvascular regulatory mechanism
Hemoglobin-based blood substitutes
Tissue oxygenation and oxygen regulation
Plasma expanders
Coagulation cascade
Intravital microscopy
Experimental model design for microvascular studies
Nitric oxide regulation and gas transport
Malaria and Tropical Deceases
Erythrocyte Biophysics
Ongoing Projects
Design and formulate plasma expanders that maximize local shear stress without increasing vascular resistance.
What are the structures involved in the mechano-transduction signal by the endothelium?
Transport of biological gases and their ability to regulate or affect cardiovascular function and cellular metabolism.
Platforms to transport and delivery of NO, CO, H2S.
To design novel therapeutic interventions to treat, manage and ultimately prevent disease using an integrative analysis of physical and chemical phenomena, based on engineering science principles and methods.
Sustain a perfused microvasculature to maximize the available oxygen carrying capacity.
Nitric Oxide (NO) supplementation for transfusion medicine.
Vascular glycocalyx.
Blood transfusion.
Oxygen carriers based on hemoglobin.
Nitric oxide (NO) regulation, and role of nitrite (NO2-).